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Post-exposure prophylaxis (PEP): my story

When I woke up realizing that I’d had unprotected sex during a one-night stand, I panicked and immediately sought out PEP.

Being on PEP (post-exposure prophylaxis) means taking anti-retroviral medicines (ARVs) after being potentially exposed to HIV to prevent becoming infected.

I consider myself sexually responsible; that is, I usually have only one sexual partner at a time. I’m a strong believer in getting tested together with a new lover and agreeing on protection for the length of the relationship. Finally, in the cases where I’ve had a one-night stand, condoms are non-negotiable. Right? Wrong, I slipped up on the worst possible occasion.

After a long work week, my colleagues and I were looking to unwind. We wanted to go out for drinks and blow off steam. I should probably mention that I wasn’t in the country. We had travelled to South Africa (SA) for the week and were working with our South African counterparts.

Fast forward: many more drinks later, after tearing up dance floors, the surviving group piled into taxis and headed back to our hotel in the wee hours of the morning.

A new friend from the SA team joined me in my room looking to extend our night of fun. One thing led to another.

‘Do you have a condom?’ I asked. He didn’t.

I asked him to go buy some from the reception. Even in my drunken desire, alarm bells were going off in my head. I remembered that SA has a huge HIV problem. Around 20 per cent of the adults are infected. Either way, I barely knew the guy. Minutes later he returned empty-handed. The hotel didn’t sell condoms. Clearly, the only thing left to do was to end the night and bid him farewell, right?

Wrong again!   

‘I haven’t had any sex since I last got tested, you?’ I asked.

He claimed he was ‘clean’ and had last checked his HIV status four months prior. Alarm bells kept ringing. The drinks had however lowered my inhibitions and we ended up having sex. It was great. I fell asleep, whilst he was leaving to catch an early flight out of the city.

‘You’ve had unprotected sex, with a stranger AND in South Africa!’

The panicked voice screaming in my head joined the pounding hangover headache and made me jump out of bed.

I acted immediately:

  1. First, I went online to see if preventive medication for HIV existed. I’d heard of victims of rape being given a form of ARVs to prevent HIV infections. This is when I came upon Post Exposure Prophylaxis.  
  2. I messaged one of my friends who is a dentist and explained my predicament seeking guidance on PEP. She advised that PEP was used only in emergency situations and must be started within 72 hours after a recent possible exposure to HIV.
  3. I found the closest medical center and went in to see a doctor. She was very reassuring and supportive of my decision to quickly seek preventive medical assistance. Just in case.
  4. Finally, I bought a small bottle containing 30 large tablets to be taken daily for a month. This would reduce the risk of contracting HIV, presuming my sexual partner was HIV-positive.

For a month, at 7:30 every night, I popped one of those tablets. The side effects weren’t as bad as I’d anticipated. Mostly pimples, bouts of nausea and unexplained exhaustion. As per the doctor’s recommendation, I took a HIV test at the end of the PEP dosage and was HIV-negative. What I do know is, the stress from wondering, ‘what if’ for all those days, was not worth any of the fun from the unprotected one night stand.

Have you had a similar experience? Share your story below or on Facebook. Our forum moderators can help with any PEP-questions you may have.


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Recent Comments (12)

  1. lyk this page so educative
    lyk this page so educative

  2. Is it possible for one to be…
    Is it possible for one to be on PEP diligently and turn out positive?
    After the one month administering of the pep, are the results conclusive or you have to wait until 3 months lapses?

    1. Hi Phil,…
      Hi Phil,

      PEP reduces the risk of HIV infection by over 80% and this is why you need to get a test after the 28 days. Most test are able to determine the correct HIV status of a person today as early as 2 weeks after exposure. The results after the 28 days should be conclusive. Remember you may only require a retest in the case where the results are HIV negative.

  3. Thanks for your earlier…
    Thanks for your earlier answer, but i am a bit confused. so if you take the PEP for 28 days and yo are found to be -ve after the 28 days, you still have to wait for 3 months to lapse after the possible exposure to get a conclusive result? the writer talked of being declared -ve after 28 days of taking the PEP,…..the waiting for me is crazy……

    1. After the 28 days, the HIV…
      After the 28 days, the HIV negative result will be a true reflection of your status. Rapid kits used today can determine the status of a person as early as 14 days.

  4. It is me again,…i have…
    It is me again,…i have just completed the 28 day PEP regimen and tested -ve. Kindly let me know for sure that i am good and the results won’t change after 3 months post exposure,…..THANKS

    1. Hi Phil, It is indeed…
      Hi Phil, It is indeed expected that your result will not change since the Window period of the current rapid test kits is 4 weeks. Other testing methods can detect the presence of the virus much earlier.

  5. Nimehave sex na mtu siko…
    Nimehave sex na mtu siko sure the ikaburst. Where can I get PEP na itakua how much?

      1. Hi there, 


        Hi there, 

        Ukienda government hospital utapata free. 

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